Circa 1968, several strangers, most with a secret to bury, meet by chance at Lake Tahoe's El Royale, a rundown hotel with a dark past. Over the course of one night, everyone will show their true colors - before everything goes to hell.
In the prehistoric past, a young man struggles to return home after being separated from his tribe during a buffalo hunt. He finds a similarly lost wolf companion and starts a friendship that would change humanity.
Set in contemporary Chicago, amid a time of turmoil, four women with nothing in common except a debt left behind by their dead husbands' criminal activities, take fate into their own hands, and conspire to forge a future on their own terms.